H4K20me3 co-localizes with activating histone modifications at transcriptionally dynamic regions in embryonic stem cells
Abstract Background Bivalent chromatin domains consisting of the activating histone 3 lysine 4 trimethylation (H3K4me3) and repressive histone 3 lysine 27 trimethylation (H3K27me3) histone modifications are enriched at developmental genes that are repressed in embryonic stem cells but active during differentiation.However, it is unknown whether ano